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1

The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

K. C. Nicolaou, Dionisios Vourloumis, Nicolas Winssinger, Phil S. Baran

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 2.84 MB

english, 2000

2

Total Synthesis of Vancomycin

K. C. Nicolaou, Helen J. Mitchell, Nareshkumar F. Jain, Nicolas Winssinger, Robert Hughes, Toshikazu Bando

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 125 KB

english, 1999

3

Totalsynthese von Vancomycin

K. C. Nicolaou, Helen J. Mitchell, Nareshkumar F. Jain, Nicolas Winssinger, Robert Hughes, Toshikazu Bando

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 113 KB

german, 1999

4

Synthesis and Biological Evaluation of Vancomycin Dimers with Potent Activity against Vancomycin-Resistant Bacteria: Target-Accelerated Combinatorial Synthesis

K. C. Nicolaou, Robert Hughes, Suk Young Cho, Nicolas Winssinger, Harald Labischinski, Rainer Endermann

Journal:

Chemistry - A European Journal

Year:

2001

Language:

english

File:

PDF, 474 KB

english, 2001

5

Modular Asymmetric Synthesis of Pochonin C

Sofia Barluenga, Pilar Lopez, Emilie Moulin, Nicolas Winssinger

Journal:

Angewandte Chemie

Year:

2004

Language:

english

File:

PDF, 140 KB

english, 2004

6

Modular Asymmetric Synthesis of Pochonin C

Sofia Barluenga, Pilar Lopez, Emilie Moulin, Nicolas Winssinger

Journal:

Angewandte Chemie International Edition

Year:

2004

Language:

english

File:

PDF, 140 KB

english, 2004

7

Solution- and Solid-Phase Synthesis of Radicicol (Monorden) and Pochonin C

Sofia Barluenga, Emilie Moulin, Pilar Lopez, Nicolas Winssinger

Journal:

Chemistry - A European Journal

Year:

2005

Language:

english

File:

PDF, 421 KB

english, 2005

8

Nucleic acid encoding to program self-assembly in chemical biology

Pianowski, Zbigniew L., Winssinger, Nicolas

Journal:

Chemical Society Reviews

Year:

2008

Language:

english

File:

PDF, 1.86 MB

english, 2008

9

Azidopeptide Nucleic Acid. An Alternative Strategy for Solid-Phase Peptide Nucleic Acid (PNA) Synthesis

Debaene, François, Winssinger, Nicolas

Journal:

Organic Letters

Year:

2003

Language:

english

File:

PDF, 92 KB

english, 2003

10

PNA-encoded chemical libraries

Zambaldo, Claudio, Barluenga, Sofia, Winssinger, Nicolas

Journal:

Current Opinion in Chemical Biology

Year:

2015

Language:

english

File:

PDF, 820 KB

english, 2015

11

Einfache Festphasensynthese von Oligosacchariden – Herstellung eines Dodecasaccharids

Kyriacos C. Nicolaou, Nobuhide Watanabe, Jim Li, Joaquín Pastor, Nicolas Winssinger

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 148 KB

german, 1998

12

Festphasensynthese von Makrocyclen mit der Strategie der Abspaltung unter Cyclisierung: Anwendung der Stille-Kupplung bei der Synthese von (S)-Zearalenon

K. C. Nicolaou, Nicolas Winssinger, Joaquin Pastor, Fiona Murphy

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 176 KB

german, 1998

13

Chemie, Biologie und medizinische Anwendungen der Glycopeptid-Antibiotika

K. C. Nicolaou, Christopher N. C. Boddy, Stefan Bräse, Nicolas Winssinger

Journal:

Angewandte Chemie

Year:

1999

Language:

german

File:

PDF, 1.43 MB

german, 1999

14

Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts

K. C. Nicolaou, Dionisios Vourloumis, Nicolas Winssinger, Phil S. Baran

Journal:

Angewandte Chemie

Year:

2000

Language:

german

File:

PDF, 2.91 MB

german, 2000

15

New Selenium-Based Safety-Catch Linkers: Solid-Phase Semisynthesis of Vancomycin

K. C. Nicolaou, Nicolas Winssinger, Robert Hughes, Christopher Smethurst, Suk Young Cho

Journal:

Angewandte Chemie

Year:

2000

Language:

english

File:

PDF, 276 KB

english, 2000

16

Total Synthesis of Vancomycin—Part 4: Attachment of the Sugar Moieties and Completion of the Synthesis

K. C. Nicolaou, Helen J. Mitchell, Nareshkumar F. Jain, Toshikazu Bando, Robert Hughes, Nicolas Winssinger, Swaminathan Natarajan, Alexandros E. Koumbis

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 418 KB

english, 1999

17

Solid-Phase Synthesis of Oligosaccharides: Construction of a Dodecasaccharide

K. C. Nicolaou, Nobuhide Watanabe, Jim Li, Joaquín Pastor, Nicolas Winssinger

Journal:

Angewandte Chemie International Edition

Year:

1998

Language:

english

File:

PDF, 146 KB

english, 1998

18

Solid-Phase Synthesis of Macrocyclic Systems by a Cyclorelease Strategy: Application of the Stille Coupling to a Synthesis of (S)-Zearalenone

K. C. Nicolaou, Nicolas Winssinger, Joaquin Pastor, Fiona Murphy

Journal:

Angewandte Chemie International Edition

Year:

1998

Language:

english

File:

PDF, 193 KB

english, 1998

19

Chemistry, Biology, and Medicine of the Glycopeptide Antibiotics

K. C. Nicolaou, Christopher N. C. Boddy, Stefan Bräse, Nicolas Winssinger

Journal:

Angewandte Chemie International Edition

Year:

1999

Language:

english

File:

PDF, 1.49 MB

english, 1999

20

New Selenium-Based Safety-Catch Linkers: Solid-Phase Semisynthesis of Vancomycin

K. C. Nicolaou, Nicolas Winssinger, Robert Hughes, Christopher Smethurst, Suk Young Cho

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 282 KB

english, 2000

21

Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria

K. C. Nicolaou, Robert Hughes, Suk Young Cho, Nicolas Winssinger, Christian Smethurst, Harald Labischinski, Rainer Endermann

Journal:

Angewandte Chemie

Year:

2000

Language:

english

File:

PDF, 195 KB

english, 2000

22

Von Split-Pool-Molekülbibliotheken zu räumlich adressierbaren Mikro-Arrays und deren Einsatz in der funktionellen Proteomik

Nicolas Winssinger, Jennifer L. Harris, Bradley J. Backes, Peter G. Schultz

Journal:

Angewandte Chemie

Year:

2001

Language:

german

File:

PDF, 213 KB

german, 2001

23

Titelbild

Nicolas Winssinger, Jennifer L. Harris, Bradley J. Backes, Peter G. Schultz

Journal:

Angewandte Chemie

Year:

2001

File:

PDF, 142 KB

2001

24

Total Synthesis of 16-Desmethylepothilone B, Epothilone B10, Epothilone F, and Related Side Chain Modified Epothilone B Analogues

K. C. Nicolaou, David Hepworth, N. Paul King, M. Raymond V. Finlay, Rita Scarpelli, M. Manuela A. Pereira, Birgit Bollbuck, Antony Bigot, Barbara Werschkun, Nicolas Winssinger

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 352 KB

english, 2000

25

Solid- and Solution-Phase Synthesis of Vancomycin and Vancomycin Analogues with Activity against Vancomycin-Resistant Bacteria

K. C. Nicolaou, Suk Young Cho, Robert Hughes, Nicolas Winssinger, Christian Smethurst, Harald Labischinski, Rainer Endermann

Journal:

Chemistry - A European Journal

Year:

2001

Language:

english

File:

PDF, 647 KB

english, 2001

26

Target-Accelerated Combinatorial Synthesis and Discovery of Highly Potent Antibiotics Effective Against Vancomycin-Resistant Bacteria

K. C. Nicolaou, Robert Hughes, Suk Young Cho, Nicolas Winssinger, Christian Smethurst, Harald Labischinski, Rainer Endermann

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 194 KB

english, 2000

27

Cover Picture

Nicolas Winssinger, Jennifer L. Harris, Bradley J. Backes, Peter G. Schultz

Journal:

Angewandte Chemie International Edition

Year:

2001

File:

PDF, 144 KB

2001

28

From Split-Pool Libraries to Spatially Addressable Microarrays and Its Application to Functional Proteomic Profiling

Nicolas Winssinger, Jennifer L. Harris, Bradley J. Backes, Peter G. Schultz

Journal:

Angewandte Chemie International Edition

Year:

2001

Language:

english

File:

PDF, 176 KB

english, 2001

29

Gezielt entworfene Epothilone: kombinatorische Synthese, Induktion der Tubulin-Polymerisation und cytotoxische Wirkung gegen taxolresistente Tumorzellen

Prof. Dr. Kyriacos Costa Nicolaou, Dr. Dionisios Vourloumis, Dr. Tianhu Li, Dr. Joaquin Pastor, Nicolas Winssinger, Yun He, Dr. Sacha Ninkovic, Dr. Francisco Sarabia, Dr. Hans Vallberg, Dr. Frank Rosc

Journal:

Angewandte Chemie

Year:

1997

Language:

german

File:

PDF, 728 KB

german, 1997

30

Modular Asymmetric Synthesis of Aigialomycin D, a Kinase-Inhibitory Scaffold

Sofia Barluenga, Pierre-Yves Dakas, Yoan Ferandin, Laurent Meijer, Nicolas Winssinger

Journal:

Angewandte Chemie

Year:

2006

Language:

english

File:

PDF, 205 KB

english, 2006

31

Modular Synthesis of Radicicol A and Related Resorcylic Acid Lactones, Potent Kinase Inhibitors

Pierre-Yves Dakas, Sofia Barluenga, Frank Totzke, Ute Zirrgiebel, Nicolas Winssinger

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 258 KB

english, 2007

32

Divergent Synthesis of a Pochonin Library Targeting HSP90 and In Vivo Efficacy of an Identified Inhibitor

Sofia Barluenga, Cuihua Wang, Jean-Gonzague Fontaine, Kaïss Aouadi, Kristin Beebe, Shinji Tsutsumi, Len Neckers, Nicolas Winssinger

Journal:

Angewandte Chemie

Year:

2008

Language:

english

File:

PDF, 563 KB

english, 2008

33

DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV

Katarzyna Gorska, Kuo-Ting Huang, Olivier Chaloin, Nicolas Winssinger

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 852 KB

english, 2009

34

Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol-Resistant Tumor Cells

Prof. Dr. K. C. Nicolaou, Dr. Dionisios Vourloumis, Dr. Tianhu Li, Dr. Joaquin Pastor, Nicolas Winssinger, Yun He, Dr. Sacha Ninkovic, Dr. Francisco Sarabia, Dr. Hans Vallberg, Dr. Frank Roschangar, D

Journal:

Angewandte Chemie International Edition

Year:

1997

Language:

english

File:

PDF, 881 KB

english, 1997

35

Modular Asymmetric Synthesis of Aigialomycin D, a Kinase-Inhibitory Scaffold

Sofia Barluenga, Pierre-Yves Dakas, Yoan Ferandin, Laurent Meijer, Nicolas Winssinger

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 205 KB

english, 2006

36

Modular Synthesis of Radicicol A and Related Resorcylic Acid Lactones, Potent Kinase Inhibitors

Pierre-Yves Dakas, Sofia Barluenga, Frank Totzke, Ute Zirrgiebel, Nicolas Winssinger

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 259 KB

english, 2007

37

Divergent Synthesis of a Pochonin Library Targeting HSP90 and In Vivo Efficacy of an Identified Inhibitor

Sofia Barluenga, Cuihua Wang, Jean-Gonzague Fontaine, Kaïss Aouadi, Kristin Beebe, Shinji Tsutsumi, Len Neckers, Nicolas Winssinger

Journal:

Angewandte Chemie International Edition

Year:

2008

Language:

english

File:

PDF, 563 KB

english, 2008

38

DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV

Katarzyna Gorska, Kuo-Ting Huang, Olivier Chaloin, Nicolas Winssinger

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 853 KB

english, 2009

39

Self-Assembled Small-Molecule Microarrays for Protease Screening and Profiling

Hugo D. Urbina, François Debaene, Bernard Jost, Christine Bole-Feysot, Daniel E. Mason, Petr Kuzmic, Jennifer L. Harris, Nicolas Winssinger

Journal:

Year:

2006

Language:

english

File:

PDF, 593 KB

english, 2006

40

Chemical Biology: From Small Molecules to Systems Biology and Drug Design. Edited by Stuart L. Schreiber, Tarun Kapoor, and Günther Wess.

Nicolas Winssinger

Journal:

Year:

2007

Language:

english

File:

PDF, 46 KB

english, 2007

41

Inhibition of HSP90 with Pochoximes: SAR and Structure-Based Insights

Sofia Barluenga, Jean-Gonzague Fontaine, Cuihua Wang, Kais Aouadi, Ruihong Chen, Kristin Beebe, Len Neckers, Nicolas Winssinger

Journal:

Year:

2009

Language:

english

File:

PDF, 640 KB

english, 2009

42

In Vivo Efficacy of Natural Product-Inspired Irreversible Kinase Inhibitors

Sofia Barluenga, Rajamalleswaramma Jogireddy, Girish K. Koripelly, Nicolas Winssinger

Journal:

Year:

2010

Language:

english

File:

PDF, 989 KB

english, 2010

43

Combinatorial Self-Assembly of Glycan Fragments into Microarrays

Kuo-Ting Huang, Katarzyna Gorska, Dr. Susana Alvarez, Dr. Sofia Barluenga, Prof. Nicolas Winssinger

Journal:

Year:

2011

Language:

english

File:

PDF, 708 KB

english, 2011

44

Diversity-Oriented Synthesis of Pochonins and Biological Evaluation against a Panel of Kinases

Emilie Moulin, Sofia Barluenga, Frank Totzke, Nicolas Winssinger

Journal:

Chemistry - A European Journal

Year:

2006

Language:

english

File:

PDF, 616 KB

english, 2006

45

Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases

Rajamalleswaramma Jogireddy, Pierre-Yves Dakas, Gaëlle Valot, Sofia Barluenga, Nicolas Winssinger

Journal:

Chemistry - A European Journal

Year:

2009

Language:

english

File:

PDF, 405 KB

english, 2009

46

Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin

Pierre-Yves Dakas, Rajamalleswaramma Jogireddy, Gaëlle Valot, Sofia Barluenga, Nicolas Winssinger

Journal:

Chemistry - A European Journal

Year:

2009

Language:

english

File:

PDF, 453 KB

english, 2009

47

Cover Picture: Divergent Syntheses of Resorcylic Acid Lactones: L-783277, LL-Z1640-2, and Hypothemycin / Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases (Chem. Eur. J. 43/2009)

Pierre-Yves Dakas, Rajamalleswaramma Jogireddy, Gaëlle Valot, Sofia Barluenga, Nicolas Winssinger

Journal:

Chemistry - A European Journal

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

48

Concise Modular Asymmetric Synthesis of Deguelin, Tephrosin and Investigation into Their Mode of Action

José Garcia, Sofia Barluenga, Kristin Beebe, Len Neckers, Nicolas Winssinger

Journal:

Chemistry - A European Journal

Year:

2010

Language:

english

File:

PDF, 384 KB

english, 2010

49

ChemInform Abstract: Total Synthesis of Vancomycin.

K. C. Nicolaou, Helen J. Mitchell, Nareshkumar F. Jain, Nicolas Winssinger, Robert Hughes, Toshikazu Bando

Journal:

Year:

1999

File:

PDF, 22 KB

1999

50

ChemInform Abstract: Synthesis of the Macrocyclic Core of Sanglifehrin A.

K. C. Nicolaou, Takashi Ohshima, Fiona Murphy, Sofia Barluenga, Jinyou Xu, Nicolas Winssinger

Journal:

Year:

1999

File:

PDF, 33 KB

1999